Palladium-catalyzed enantioselective addition of two distinct nucleophiles across alkenes capable of quinone methide formation.
J Am Chem Soc
; 131(47): 17074-5, 2009 Dec 02.
Article
en En
| MEDLINE
| ID: mdl-19902942
A sequential intramolecular-intermolecular enantioselective alkene difunctionalization reaction has been developed which is thought to proceed through Pd-catalyzed quinone methide formation. The synthesis of new chiral heterocyclic compounds with adjacent chiral centers is achieved in enantiomeric ratios up to 99:1 and diastereomeric ratios up to 10:1.
Texto completo:
1
Colección:
01-internacional
Base de datos:
MEDLINE
Asunto principal:
Paladio
/
Indolquinonas
/
Alquenos
Idioma:
En
Revista:
J Am Chem Soc
Año:
2009
Tipo del documento:
Article
País de afiliación:
Estados Unidos
Pais de publicación:
Estados Unidos