Genetic associations of prolactin increase in olanzapine/fluoxetine combination-treated patients.
Psychiatry Res
; 175(1-2): 171-2, 2010 Jan 30.
Article
en En
| MEDLINE
| ID: mdl-19896213
In patients from two clinical trials, we investigated the associations of single nucleotide polymorphisms (SNPs) in candidate genes with prolactin level changes during treatment with olanzapine/fluoxetine combination. In both cohorts, three dopamine receptor D2 (DRD2) SNPs were associated with prolactin changes. DRD2 may influence susceptibility to hyperprolactinemia associated with antipsychotic treatment.
Texto completo:
1
Colección:
01-internacional
Base de datos:
MEDLINE
Asunto principal:
Prolactina
/
Antipsicóticos
/
Benzodiazepinas
/
Hiperprolactinemia
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Fluoxetina
/
Receptores de Dopamina D2
/
Polimorfismo de Nucleótido Simple
Tipo de estudio:
Clinical_trials
/
Risk_factors_studies
Límite:
Adult
/
Aged
/
Female
/
Humans
/
Male
/
Middle aged
Idioma:
En
Revista:
Psychiatry Res
Año:
2010
Tipo del documento:
Article
País de afiliación:
Estados Unidos
Pais de publicación:
Irlanda