Neopentylglycolborylation of aryl chlorides catalyzed by the mixed ligand system NiCl2(dppp)/dppf.

Moldoveanu, Costel; Wilson, Daniela A; Wilson, Christopher J; Corcoran, Patrick; Rosen, Brad M; Percec, Virgil

Moldoveanu, Costel; Wilson, Daniela A; Wilson, Christopher J; Corcoran, Patrick; Rosen, Brad M; Percec, Virgil.

Afiliación

Moldoveanu C; Roy & Diana Vagelos Laboratories, Department of Chemistry, University of Pennsylvania, Philadelphia, Pennsylvania 19104-6323, USA.

Org Lett ; 11(21): 4974-7, 2009 Nov 05.

Article en En | MEDLINE | ID: mdl-19863151

RESUMEN

The mixed ligand system 10 mol % NiCl(2)(dppp) with 5 mol % dppf was discovered to be an extremely efficient catalyst for the neopentylglycolborylation of a diversity of electron-rich and electron-deficient aryl chlorides. Optimization showed that 5 mol % catalyst with 10% dppf was even more efficient. These results highlight the complexity of the relationship between catalyst and coligand in Ni catalysis and the benefit of combinations of mixed ligand in catalyst design.

Asunto(s)

Canfanos/química; Técnicas Químicas Combinatorias; Hidrocarburos Clorados/química; Níquel/química; Catálisis; Ligandos; Estructura Molecular

Texto completo

Añadir a Mi BVS

Imprimir

XML

PubMed Links

Buscar en Google

Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Canfanos / Técnicas Químicas Combinatorias / Hidrocarburos Clorados / Níquel Idioma: En Revista: Org Lett Asunto de la revista: BIOQUIMICA Año: 2009 Tipo del documento: Article País de afiliación: Estados Unidos Pais de publicación: Estados Unidos

Texto completo

Añadir a Mi BVS

Imprimir

XML

PubMed Links

Buscar en Google