[125I]deoxycytidine used in a rapid, sensitive, and specific assay for herpes simplex virus type 1 thymidine kinase.
J Virol
; 24(1): 314-8, 1977 Oct.
Article
en En
| MEDLINE
| ID: mdl-198581
[125I]deoxycytidine was a good substrate for herpes simplex virus type 1 thymidine kinase (TK), whereas [125I]deoxycytidine was a very poor substrate for cellular TK. Simple, sensitive, and specific assays for viral TK could be carried out in vivo and in vitro even in the presence of cell TK. Autoradiographic detection of incorporated [125I]deoxycytidine provided a rapid and simple method for detection of and screening for viral TK in infected as well as viral TK-transformed cells.
Texto completo:
1
Colección:
01-internacional
Base de datos:
MEDLINE
Asunto principal:
Timidina Quinasa
/
Simplexvirus
/
Desoxicitidina
Tipo de estudio:
Diagnostic_studies
Idioma:
En
Revista:
J Virol
Año:
1977
Tipo del documento:
Article
Pais de publicación:
Estados Unidos