Pregnancy outcome of women transfused during pregnancy with blood products inadvertently obtained from donors treated with acitretin.
J Obstet Gynaecol
; 29(8): 694-7, 2009 Nov.
Article
en En
| MEDLINE
| ID: mdl-19821659
We assessed the pregnancy outcome of nine women inadvertently transfused with acitretin-contaminated blood products in South Korea. A total of 18 women matched to cases by age, gravidity, and singleton- or twin-pregnancy, and who were transfused with blood products not contaminated with acitretin, was also recruited. There were nine babies born in the case group. No differences (p > 0.05) were observed between cases and controls in the gestational age at delivery (38.3 +/- 1.6 weeks vs 37.8 +/- 2.2 weeks), birth weight (3,146 +/- 874 g vs 3,106 +/- 568 g), rate of pre-term deliveries (22.2% vs 11.1%) and rate of low birth weight (<2,500 g) (33.3% vs 16.7%). There was no case of malformation or neurological abnormalities born in either group. In conclusion, inadvertent exposure to acitretin-contaminated blood products was not associated with adverse pregnancy outcomes, probably because of the removal of acitretin and etretinate during the manufacturing process of blood products.
Texto completo:
1
Colección:
01-internacional
Base de datos:
MEDLINE
Asunto principal:
Productos Biológicos
/
Resultado del Embarazo
/
Acitretina
/
Reacción a la Transfusión
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Queratolíticos
Tipo de estudio:
Observational_studies
/
Risk_factors_studies
Límite:
Adult
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Female
/
Humans
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Newborn
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Pregnancy
Idioma:
En
Revista:
J Obstet Gynaecol
Año:
2009
Tipo del documento:
Article
Pais de publicación:
Reino Unido