Cutaneous melanoma with metastasis in a cynomolgus monkey (Macaca fascicularis).

Pellegrini, G; Bienvenu, J G; Meehan, J T; Mischler, S A; Perry, R W; Scott, D W; Anderson, W I

Pellegrini, G; Bienvenu, J G; Meehan, J T; Mischler, S A; Perry, R W; Scott, D W; Anderson, W I.

Afiliación

Pellegrini G; Wyeth Research, Catania, Italy. pellegg@wyeth.com

J Med Primatol ; 38(6): 444-7, 2009 Dec.

Article en En | MEDLINE | ID: mdl-19793176

RESUMEN

BACKGROUND: A 3.3-year-old-male cynomolgus macaque (Macaca fascicularis) showed a focally extensive soft, dark, discoid dermal mass, 0.5 cm in diameter, on the dorsal surface of the right hind foot, over the fourth and fifth metatarsal bones. METHODS AND RESULTS Microscopic examination revealed a cutaneous melanoma with local lymphatic invasion, characterized by neoplastic melanocytes within the subcapsular sinus of popliteal and inguinal lymph nodes. The diagnosis was confirmed by immunohistochemistry and transmission electron microscopy. CONCLUSIONS: To our knowledge, this is the first documented case of melanoma in a cynomolgus monkey.

Asunto(s)

Macaca fascicularis; Melanoma/patología; Neoplasias Cutáneas/patología; Piel/patología; Animales; Metástasis Linfática; Masculino

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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Piel / Neoplasias Cutáneas / Macaca fascicularis / Melanoma Límite: Animals Idioma: En Revista: J Med Primatol Año: 2009 Tipo del documento: Article País de afiliación: Italia Pais de publicación: Dinamarca

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