Generation of chromosome size polymorphism during in vivo mitotic multiplication of Plasmodium berghei involves both loss and addition of subtelomeric repeat sequences.
Mol Biochem Parasitol
; 41(1): 73-82, 1990 Jun.
Article
en En
| MEDLINE
| ID: mdl-1974695
Extensive chromosome size polymorphism arises in Plasmodium berghei during in vivo mitotic multiplication. Size differences between homologous chromosomes involve rearrangements occurring in the subtelomeric portions while internal chromosomal regions do not contribute significantly to chromosome size polymorphism. Differences in the copy number of a 2.3-kb subtelomeric repeated unit are shown to correlate with size variations, and in at least one case to account completely for the size difference between two variants of the same chromosome.
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Colección:
01-internacional
Base de datos:
MEDLINE
Asunto principal:
Plasmodium berghei
/
Polimorfismo de Longitud del Fragmento de Restricción
/
Secuencias Repetitivas de Ácidos Nucleicos
/
Cromosomas
/
Mitosis
Límite:
Animals
Idioma:
En
Revista:
Mol Biochem Parasitol
Año:
1990
Tipo del documento:
Article
País de afiliación:
Italia
Pais de publicación:
Países Bajos