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Golfieri, R; Marini, E; Bazzocchi, A; Fusco, F; Trevisani, F; Sama, C; Mazzella, G; Cavuto, S; Piscaglia, F; Bolondi, L.
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  • Golfieri R; Radiologia Malpighi, Azienda Ospedaliero-Universitaria di Bologna, Policlinico S. Orsola-Malpighi, Università di Bologna, Via Albertoni 15, 40138, Bologna, Italy. Rita.golfieri@aosp.bo.it
Radiol Med ; 114(8): 1239-66, 2009 Dec.
Article en En | MEDLINE | ID: mdl-19697104
PURPOSE: We prospectively compared gadoliniumenhanced magnetic resonance imaging (dynamic MRI), superparamagnetic iron oxide (SPIO) (ferucarbotran) MRI and multidetector-row computed tomography (MDCT) and the combination of dynamic MRI plus MDCT vs. dynamic MRI plus SPIO-MRI (double-contrast MRI: DC-MRI) for the detection of small (1 cm and the highest specificity (83.3%) superior to dynamic MRI (p<0.0001). In the per-lesion analysis, SPIO-MRI demonstrated a positive predictive value higher than dynamic MRI (p=0.0059) and than both the combinations dynamic MRI/MDCT and DC-MRI (p=0.0021 and p=0.0087, respectively). DC-MRI showed the highest sensitivity (97.7%) and accuracy (78.9%), detecting hypovascular and atypical HCCs >1 cm. Furthermore its per-patient negative predictive value was the highest (100%), and significantly higher than all the other methods. CONCLUSIONS: DC-MRI is the most sensitive and accurate method and can be confidently used as a single-step procedure for the detection of small HCCs, with the exception of lesions <1 cm.
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Imagen por Resonancia Magnética / Tomografía Computarizada por Rayos X / Carcinoma Hepatocelular / Medios de Contraste / Cirrosis Hepática / Neoplasias Hepáticas Tipo de estudio: Diagnostic_studies / Observational_studies / Prognostic_studies / Risk_factors_studies Límite: Adult / Aged / Aged80 / Female / Humans / Male / Middle aged Idioma: En Revista: Radiol Med Año: 2009 Tipo del documento: Article País de afiliación: Italia Pais de publicación: Italia
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Imagen por Resonancia Magnética / Tomografía Computarizada por Rayos X / Carcinoma Hepatocelular / Medios de Contraste / Cirrosis Hepática / Neoplasias Hepáticas Tipo de estudio: Diagnostic_studies / Observational_studies / Prognostic_studies / Risk_factors_studies Límite: Adult / Aged / Aged80 / Female / Humans / Male / Middle aged Idioma: En Revista: Radiol Med Año: 2009 Tipo del documento: Article País de afiliación: Italia Pais de publicación: Italia