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Economic evaluation of antipsychotic drugs for schizophrenia treatment within the Brazilian Healthcare System.
Lindner, Leandro Mendonça; Marasciulo, Antonio Carlos; Farias, Mareni Rocha; Grohs, Geder Evandro Motta.
Afiliación
  • Lindner LM; Programa de Pós-Graduação em Farmácia, Universidade Federal de Santa Catarina (UFSC), 88040-970 Florianópolis, SC, Brasil.
Rev Saude Publica ; 43 Suppl 1: 62-9, 2009 Aug.
Article en En | MEDLINE | ID: mdl-19669066
OBJECTIVE: To assess the cost-utility of first and second-generation antipsychotics for treatment of schizophrenia. METHODS: A five-year Markov model was constructed based on a survey of the records of patients seen in 2006 at a psychosocial care center in the municipality of Florianopolis, Southern Brazil. Costs were evaluated from the perspective of the Sistema Unico de Saúde (SUS - Unified Healthcare System). Utility was measured in quality-adjusted life years obtained in the literature. RESULTS: The Markov model indicated risperidone and haloperidol utilization before olanzapine as the most cost-effective alternatives. CONCLUSIONS: Antipsychotic agents haloperidol and risperidone are more cost-effective than olanzapine. Strategies prioritizing the use of antipsychotics with better cost-effectiveness could optimize resource allocation without necessarily compromising the health of patients treated through the Sistema Unico de Saúde.
Asunto(s)

Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Esquizofrenia / Antipsicóticos / Benzodiazepinas / Costos de los Medicamentos / Risperidona / Haloperidol Tipo de estudio: Evaluation_studies / Health_economic_evaluation Aspecto: Patient_preference Límite: Humans País/Región como asunto: America do sul / Brasil Idioma: En Revista: Rev Saude Publica Año: 2009 Tipo del documento: Article País de afiliación: Brasil Pais de publicación: Brasil

Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Esquizofrenia / Antipsicóticos / Benzodiazepinas / Costos de los Medicamentos / Risperidona / Haloperidol Tipo de estudio: Evaluation_studies / Health_economic_evaluation Aspecto: Patient_preference Límite: Humans País/Región como asunto: America do sul / Brasil Idioma: En Revista: Rev Saude Publica Año: 2009 Tipo del documento: Article País de afiliación: Brasil Pais de publicación: Brasil