An approach to peripheral vasodilator-beta-adrenergic blocking agents.
J Med Chem
; 20(8): 1024-9, 1977 Aug.
Article
en En
| MEDLINE
| ID: mdl-19628
The syntheses of 2-phenyl- and 2-pyridyl-4-trifluoromethylimidazoles having a 3-tert-butylamino-2-hydroxypropoxy moiety attached to the aryl or heteroaryl substituent are described. Structure--activity relationships based on results from an evaluation of these compounds for antihypertensive, vasodilating, and beta-adrenergic blocking activities are discussed.
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Colección:
01-internacional
Base de datos:
MEDLINE
Asunto principal:
Vasodilatadores
/
Antagonistas Adrenérgicos beta
/
Imidazoles
Límite:
Animals
Idioma:
En
Revista:
J Med Chem
Asunto de la revista:
QUIMICA
Año:
1977
Tipo del documento:
Article
Pais de publicación:
Estados Unidos