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[Analysis of prognostic factors in 300 colorectal cancer patients with liver metastases].
Fang, Hua; Wang, Xing-yuan; Wang, Jin-wan; Zhang, Hong-gang; Feng, Feng-yi; Shi, Yuan-kai.
Afiliación
  • Fang H; Department of Medical Oncology, Chinese Academy of Medical Sciences, Beijing 100021, China.
Zhonghua Zhong Liu Za Zhi ; 31(3): 220-2, 2009 Mar.
Article en Zh | MEDLINE | ID: mdl-19615265
OBJECTIVE: To analyse the clinical characteristics and potential prognostic factors of colorectal cancer patients with liver metastases. METHODS: The clinical and pathological data of 300 colorectal cancer patients with liver metastases were retrospectively reviewed and analyzed. RESULTS: The median survival time of these patients was 19.0 months. The 1-, 2- and 5-year survival rates after liver metastases were 79.0%, 29.0% and 3.0%, respectively. Univariate analysis revealed that performance status (KPS), histological grading, primary tumor, N status, lymphatic and vascular invasion, stage at diagnosis, the number, size and distribution of liver metastases and other accompanied metastases were prognostic factors. Multivariate analysis showed that KPS, lymphatic and vascular invasion, the number and size of liver metastases were independent prognostic factors of colorectal cancer with liver metastases. CONCLUSION: Performance status, lymphatic and vascular invasion, the number and size of liver metastases are independent prognostic factors of colorectal cancer with liver metastases.
Asunto(s)
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Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Neoplasias del Recto / Adenocarcinoma / Neoplasias del Colon / Neoplasias Hepáticas Tipo de estudio: Observational_studies / Prognostic_studies / Risk_factors_studies Límite: Adult / Aged / Aged80 / Female / Humans / Male / Middle aged Idioma: Zh Revista: Zhonghua Zhong Liu Za Zhi Año: 2009 Tipo del documento: Article País de afiliación: China Pais de publicación: China
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Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Neoplasias del Recto / Adenocarcinoma / Neoplasias del Colon / Neoplasias Hepáticas Tipo de estudio: Observational_studies / Prognostic_studies / Risk_factors_studies Límite: Adult / Aged / Aged80 / Female / Humans / Male / Middle aged Idioma: Zh Revista: Zhonghua Zhong Liu Za Zhi Año: 2009 Tipo del documento: Article País de afiliación: China Pais de publicación: China