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[Retrospective analysis of maternal and infant birth features of hepatoblastoma patients].
Pu, Cong-lun; Guo, Chun-bao; Jin, Xian-qing; Deng, Chun; Zhang, Ming-man; Li, Ying-cun; Kang, Quan.
Afiliación
  • Pu CL; Department of Hepatobiliary Surgery, Children's Hospital, Chongqing Medical University, Chongqing, China.
Zhonghua Gan Zang Bing Za Zhi ; 17(6): 459-61, 2009 Jun.
Article en Zh | MEDLINE | ID: mdl-19567028
OBJECTIVE: To explore the risk factors for hepatoblastoma. METHODS: A case-cohort study using Logistic regression multiple variables analysis of medical record data sets was conducted to examine infant and perinatal risk factors for hepatoblastoma. RESULTS: Birth weight less than 1,000 g was associated with a strongly increased risk of hepatoblastoma (odds risk, OR = 26.0, 95% confidence interval, CI: 14.0 to 65.7). After adjustment of birth weight, a moderately increased risk of hepatoblastoma was found for older maternal age ( > 35 years vs. 20 to 34 years: OR = 2.6, 95% CI: 0.9 to 5.9), maternal smoking (OR = 2.9, 95% CI: 1.1 to 4.2) and higher maternal pregnancy body mass index (OR = 3.2, 95% CI: 1.0 to 6.7). CONCLUSION: Very low birth weight and maternal characteristics including overweight, smoking are associated with hepatoblastoma risk.
Asunto(s)
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Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Hepatoblastoma / Recién Nacido de muy Bajo Peso / Sobrepeso / Neoplasias Hepáticas Tipo de estudio: Etiology_studies / Observational_studies / Prognostic_studies / Risk_factors_studies Límite: Child / Child, preschool / Female / Humans / Infant / Male / Newborn / Pregnancy Idioma: Zh Revista: Zhonghua Gan Zang Bing Za Zhi Asunto de la revista: GASTROENTEROLOGIA Año: 2009 Tipo del documento: Article País de afiliación: China Pais de publicación: China
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Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Hepatoblastoma / Recién Nacido de muy Bajo Peso / Sobrepeso / Neoplasias Hepáticas Tipo de estudio: Etiology_studies / Observational_studies / Prognostic_studies / Risk_factors_studies Límite: Child / Child, preschool / Female / Humans / Infant / Male / Newborn / Pregnancy Idioma: Zh Revista: Zhonghua Gan Zang Bing Za Zhi Asunto de la revista: GASTROENTEROLOGIA Año: 2009 Tipo del documento: Article País de afiliación: China Pais de publicación: China