Etiology of acute undifferentiated febrile illness in the Amazon basin of Ecuador.
Am J Trop Med Hyg
; 81(1): 146-51, 2009 Jul.
Article
en En
| MEDLINE
| ID: mdl-19556580
We conducted a longitudinal observational study of 533 patients presenting to two hospitals in the Ecuadorean Amazon basin with acute undifferentiated febrile illness (AUFI) from 2001 through 2004. Viral isolation, reverse transcription-polymerase chain reaction (RT-PCR), IgM seroconversion, and malaria smears identified pathogens responsible for fever in 122 (40.1%) of 304 patients who provided both acute and convalescent blood samples. Leptospirosis was found in 40 (13.2%), malaria in 38 (12.5%), rickettsioses in 18 (5.9%), dengue fever in 16 (5.3%), Q fever in 15 (4.9%), brucellosis in 4 (1.3%), Ilhéus infection in 3 (1.0%), and Venezuelan equine encephalitis (VEE), Oropouche, and St. Louis encephalitis virus infections in less than 1% of these patients. Viral isolation and RT-PCR on another 229 participants who provided only acute samples identified 3 cases of dengue fever, 2 of VEE, and 1 of Ilhéus. None of these pathogens, except for malaria, had previously been detected in the study area.
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Colección:
01-internacional
Base de datos:
MEDLINE
Asunto principal:
Fiebre
Tipo de estudio:
Etiology_studies
/
Observational_studies
Límite:
Adolescent
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Adult
/
Aged
/
Child
/
Child, preschool
/
Humans
/
Infant
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Middle aged
/
Newborn
País/Región como asunto:
America do sul
/
Ecuador
Idioma:
En
Revista:
Am J Trop Med Hyg
Año:
2009
Tipo del documento:
Article
País de afiliación:
Estados Unidos
Pais de publicación:
Estados Unidos