[Diffuse alveolar hemorrhage in systemic lupus erythematosus].
Zhonghua Yi Xue Za Zhi
; 89(3): 201-3, 2009 Jan 20.
Article
en Zh
| MEDLINE
| ID: mdl-19537040
OBJECTIVE: To determine the clinical features of systemic lupus erythematosus (SLE) patients with diffuse alveolar hemorrhage (DAH). METHODS: The medical records of seventeen SLE patients with DAH were reviewed. RESULTS: Hypoxemia (100%), dyspnea (88%), cough (88%) and fever (82%) were the most common symptoms instead of hemoptysis (71%). The most common extrapulmonary presentation was renal involvement (94%). About 60% patients were complicated with lung infection. The mean drop in hemoglobin was (32 +/- 11.3) g/L. Mean SLEDAI was (17 +/- 10). All received high-dose steroids and most also were given cyclophosphamide. Ratio of mechanical ventilation in non-survivors was higher than that of survivors (P < 0.05). CONCLUSIONS: DAH is a rare and catastrophic event in SLE. DAH can occur in any course, which suggests active SLE, and frequently complicated with lupus nephritis. Some patients may have no hemoptysis.
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Colección:
01-internacional
Base de datos:
MEDLINE
Asunto principal:
Alveolos Pulmonares
/
Hemorragia
/
Lupus Eritematoso Sistémico
Tipo de estudio:
Diagnostic_studies
Límite:
Adolescent
/
Adult
/
Child
/
Female
/
Humans
/
Male
/
Middle aged
Idioma:
Zh
Revista:
Zhonghua Yi Xue Za Zhi
Año:
2009
Tipo del documento:
Article
País de afiliación:
China
Pais de publicación:
China