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[Anastomotic leakage following bowel resections for colon cancer: multivariate analysis of risk factors]. / Anastomoseninsuffizienzen nach Kolonkarzinomresektionen : Multiple Analyse der Risikofaktoren.
Kube, R; Mroczkowski, P; Steinert, R; Sahm, M; Schmidt, U; Gastinger, I; Lippert, H.
Afiliación
  • Kube R; Klinik für Allgemein-, Viszeral- und Gefässchirurgie, Universitätsklinikum A.ö.R., Leipziger Strasse 44, Magdeburg, Germany. rainer.kube@med.ovgu.de
Chirurg ; 80(12): 1153-9, 2009 Dec.
Article en De | MEDLINE | ID: mdl-19533064
BACKGROUND: The aim of this study was to evaluate the incidence and risk factors associated with anastomotic leakage after colon cancer surgery using data compiled in the nationwide German qualitative multi-center study "Colon/Rectum Cancer" (WGCRC). METHODS: From 01/01/2000 to 12/31/2004 data recorded from patients with anastomotic leakages were evaluated to determine independent predictors of leakage using logistic regression analysis. RESULTS: A total of 28,271 patients underwent colon resection with anastomoses and anastomotic leaks occurred in 3.0% (n=844). Multivariate analysis identified long duration of surgery, a high ASA score, male gender, obstruction, left-sided tumor, cardiovascular hepatic comorbidity, single-layer hand suture, anastomoses using the biofragmentable Valtrac ring, intraoperative complications and BMI>30 kg/m(2) as risk factors for postoperative occurrence of anastomotic leakage. CONCLUSIONS: Even though the rate of anastomotic leaks in patients with anastomoses after resection for colon cancer is low, it remains a significant complication, associated with significant morbidity and mortality. The knowledge of risk factors should be considered in perioperative decision-making regarding anastomotic technique and indications for Hartmann's procedure.
Asunto(s)

Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Complicaciones Posoperatorias / Dehiscencia de la Herida Operatoria / Neoplasias del Colon Tipo de estudio: Clinical_trials / Etiology_studies / Prognostic_studies / Qualitative_research / Risk_factors_studies Límite: Aged / Female / Humans / Male / Middle aged País/Región como asunto: Europa Idioma: De Revista: Chirurg Año: 2009 Tipo del documento: Article País de afiliación: Alemania Pais de publicación: Alemania

Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Complicaciones Posoperatorias / Dehiscencia de la Herida Operatoria / Neoplasias del Colon Tipo de estudio: Clinical_trials / Etiology_studies / Prognostic_studies / Qualitative_research / Risk_factors_studies Límite: Aged / Female / Humans / Male / Middle aged País/Región como asunto: Europa Idioma: De Revista: Chirurg Año: 2009 Tipo del documento: Article País de afiliación: Alemania Pais de publicación: Alemania