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Effects of cholinotropic and cytostatic drugs on the development of Arthus reaction.
Nezhinskaya, G I; Sapronov, N S; Vladykin, A L; Shepeleva, V V.
Afiliación
  • Nezhinskaya GI; S. V. Anichkov Department of Neuropharmacology, Institute of Experimental Medicine, the Russian Academy of Medical Sciences, St. Petersburg, Russia. sns@iem.spb.ru
Bull Exp Biol Med ; 146(6): 747-9, 2008 Dec.
Article en En, Ru | MEDLINE | ID: mdl-19513373
Antimuscarinic effects of ipratropium bromide and atropine are associated with prevention of the development of Arthus reaction, while the cytostatic effects of cyclophosphamide and doxorubicin lead to involution of the thymus and spleen, suppression of antibody production, and aggravation of inflammation, which causes edema of the ankle joint (cyclophosphamide treatment). Apoptosis of tumor cell and inhibition of inflammation can be essential for chemotherapy of malignant and autoimmune diseases.
Asunto(s)
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Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Reacción de Arthus / Antagonistas Colinérgicos / Agonistas Colinérgicos Límite: Animals Idioma: En / Ru Revista: Bull Exp Biol Med Año: 2008 Tipo del documento: Article País de afiliación: Rusia Pais de publicación: Estados Unidos
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Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Reacción de Arthus / Antagonistas Colinérgicos / Agonistas Colinérgicos Límite: Animals Idioma: En / Ru Revista: Bull Exp Biol Med Año: 2008 Tipo del documento: Article País de afiliación: Rusia Pais de publicación: Estados Unidos