Hemophagocytic syndrome: a cause of pancytopenia in human ehrlichiosis.

Abbott, K C; Vukelja, S J; Smith, C E; McAllister, C K; Konkol, K A; O'Rourke, T J; Holland, C J; Ristic, M

Abbott, K C; Vukelja, S J; Smith, C E; McAllister, C K; Konkol, K A; O'Rourke, T J; Holland, C J; Ristic, M.

Afiliación

Abbott KC; Department of Medicine, Brooke Army Medical Center, Fort Sam Houston, Texas 78234-6200.

Am J Hematol ; 38(3): 230-4, 1991 Nov.

Article en En | MEDLINE | ID: mdl-1951324

RESUMEN

A 67-year-old white man with human ehrlichiosis infection complicated by pancytopenia, hemophagocytic syndrome, disseminated intravascular coagulopathy and septic shock is presented. The patient had been on a three-week camping trip to California, Colorado, Utah, and New Mexico. The diagnosis of human ehrlichiosis was confirmed by sixteen-fold rise in antibody titer to Ehrlichia canis, and supported by the characteristic cytoplasmic inclusions. Human ehrlichiosis should be considered in the differential diagnosis in patients with fever and cytopenia associated with hemophagocytosis. Pancytopenia associated with ehrlichiosis is transient; however, it may be severe, and appears to be associated with destruction of normal blood elements.

Asunto(s)

Ehrlichiosis/complicaciones; Histiocitosis de Células no Langerhans/etiología; Pancitopenia/etiología; Anciano; Anticuerpos Antibacterianos/análisis; Recuento de Células Sanguíneas; Médula Ósea/patología; Histiocitosis de Células no Langerhans/microbiología; Histiocitosis de Células no Langerhans/patología; Humanos; Masculino; Pancitopenia/sangre

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Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Pancitopenia / Histiocitosis de Células no Langerhans / Ehrlichiosis Límite: Aged / Humans / Male Idioma: En Revista: Am J Hematol Año: 1991 Tipo del documento: Article Pais de publicación: Estados Unidos

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