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More than skin deep: atherosclerosis as a systemic manifestation of psoriasis.
Alexandroff, A B; Pauriah, M; Camp, R D R; Lang, C C; Struthers, A D; Armstrong, D J.
Afiliación
  • Alexandroff AB; Department of Dermatology, Leicester Royal Infirmary, Leicester LE1 5WW, UK. anton.alexandroff@gmail.com
Br J Dermatol ; 161(1): 1-7, 2009 Jul.
Article en En | MEDLINE | ID: mdl-19500102
There is now growing evidence that psoriasis, like other inflammatory diseases such as rheumatoid arthritis and systemic lupus erythematosus, is a systemic disorder that is associated with enhanced atherosclerosis and risk of coronary artery disease. Here we summarize the available epidemiological evidence for this association and analyse pathogenic features that are common to psoriasis and atherosclerosis. Further prospective studies are urgently needed to extend knowledge of the risk of cardiovascular morbidity and mortality in patients with psoriasis and to confirm the degree to which treatment of psoriasis reduces this risk. Nevertheless, existing data are sufficient to indicate that severe psoriasis should be more widely recognized as a potential risk factor for cardiovascular disease and should be considered with the established factors when formulating strategies for the management of cardiovascular risk.
Asunto(s)

Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Psoriasis / Aterosclerosis Tipo de estudio: Etiology_studies / Observational_studies / Risk_factors_studies Límite: Humans Idioma: En Revista: Br J Dermatol Año: 2009 Tipo del documento: Article Pais de publicación: Reino Unido

Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Psoriasis / Aterosclerosis Tipo de estudio: Etiology_studies / Observational_studies / Risk_factors_studies Límite: Humans Idioma: En Revista: Br J Dermatol Año: 2009 Tipo del documento: Article Pais de publicación: Reino Unido