[Predictive value of interleukin 6 from the umbilical cord blood in early neonatal infection]. / Prediktivna vrijednost Interleukina 6 iz krvi pupcanika u ranoj novorodenackoj infekciji.
Med Arh
; 63(1): 4-8, 2009.
Article
en Bs
| MEDLINE
| ID: mdl-19419117
We have analyzed diagnostic value of interleukin 6 (IL-6) from the umbilical cord blood in recognition of early neonatal infection (ENI) of newborns whose mothers have obstetrical risks. The study included 120 newborns with birth weight <2500 gr., gestational age from 37 to 42 weeks, which mothers had some of the obstetrical risks. We established three groups: group A (newborns with microbiological proof of ENI), group B (clinical signs and hematological parameters of ENI) and group C (newborns without ENI). Median of IL-6 value in group A was 48.5 pg/ml with sensitivity, specificity and diagnostic value in recognition of ENI 78%, 81% and 80%. In group B median of IL-6 was 49 pg/ml with sensitivity, specificity and diagnostic value 65%, 80% and 77%. In group C median of IL-6 was 9.7 pg/ml. We noticed significant connection between value of IL-6 and mother's urinary tract infection; group A (p=0.023), group B (p = 0.007). Also there was a remarkable relationship between mother's colpitis and level of IL-6 in newborn with ENI in group A (p=0.011) and group B (p = 0.012). High levels of IL-6 in umbilical cord blood can help us in recognition of newborns that are endangered by infection and they are clearly connected with some of mother's obstetrical risks.
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Colección:
01-internacional
Base de datos:
MEDLINE
Asunto principal:
Interleucina-6
/
Sangre Fetal
/
Infecciones
Tipo de estudio:
Diagnostic_studies
/
Etiology_studies
/
Prognostic_studies
/
Risk_factors_studies
Límite:
Female
/
Humans
/
Male
/
Newborn
/
Pregnancy
Idioma:
Bs
Revista:
Med Arh
Año:
2009
Tipo del documento:
Article
Pais de publicación:
Bosnia-Herzegovina