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Nephroprotective and clinical potential of statins in dialyzed patients.
Rysz, Jacek; Aronow, Wilbert S; Stolarek, Robert S; Hannam, Simon; Mikhailidis, Dimitri P; Banach, Maciej.
Afiliación
  • Rysz J; Medical University of Lodz, Department of Nephrology, Hypertension and Family Medicine, Lodz, Poland.
Expert Opin Ther Targets ; 13(5): 541-50, 2009 May.
Article en En | MEDLINE | ID: mdl-19368496
BACKGROUND: The combination of increased cardiovascular mortality and vascular complications due to dyslipidaemia in chronic kidney disease (CKD) has focused attention onto the potential beneficial effects of 3-hydroxy-3-methylglutaryl-coenzyme A reductase (HMG-CoA) inhibitors (statins) on the course of CKD. OBJECTIVE: To examine the use of statins in CKD. METHODS: A review of relevant literature. RESULTS/CONCLUSION: Current evidence from clinical trials in CKD patients on maintenance dialysis is limited. Therefore, the routine use of statins in this population remains the decision of individual physicians in discussion with their patients.
Asunto(s)

Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Diálisis Renal / Inhibidores de Hidroximetilglutaril-CoA Reductasas / Fallo Renal Crónico Tipo de estudio: Clinical_trials / Etiology_studies / Prognostic_studies Idioma: En Revista: Expert Opin Ther Targets Asunto de la revista: TERAPEUTICA Año: 2009 Tipo del documento: Article País de afiliación: Polonia Pais de publicación: Reino Unido

Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Diálisis Renal / Inhibidores de Hidroximetilglutaril-CoA Reductasas / Fallo Renal Crónico Tipo de estudio: Clinical_trials / Etiology_studies / Prognostic_studies Idioma: En Revista: Expert Opin Ther Targets Asunto de la revista: TERAPEUTICA Año: 2009 Tipo del documento: Article País de afiliación: Polonia Pais de publicación: Reino Unido