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Homogeneous time-resolved fluoroimmunoassay for the measurement of midregional proadrenomedullin in plasma on the fully automated system B.R.A.H.M.S KRYPTOR.
Caruhel, Pascaline; Mazier, Christian; Kunde, Jan; Morgenthaler, Nils G; Darbouret, Bruno.
Afiliación
  • Caruhel P; Research and Development Department, CEZANNE SAS, Parc Scientifique Georges Besse, Nimes Cedex 1, France. pcaruhel@cezanne.fr
Clin Biochem ; 42(7-8): 725-8, 2009 May.
Article en En | MEDLINE | ID: mdl-19318039
OBJECTIVES: Evaluate the first automated assay measuring a mid regional fragment of the proadrenomedullin (MR-proADM). DESIGN AND METHODS: B.R.A.H.M.S MR-proADM KRYPTOR is a homogeneous assay. RESULTS: In 144 healthy individuals, MR-proADM mean (SD) was measured at 0.37 nmol/L (0.09). High correlation with the manual assay, B.R.A.H.M.S MR-proADM LIA, was found on 281 samples from patients suffering from community acquired pneumonia (correlation coefficient 0.97). CONCLUSIONS: This fast assay can be used in low respiratory tract infections.
Asunto(s)

Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Precursores de Proteínas / Fluoroinmunoensayo / Adrenomedulina Límite: Adult / Female / Humans / Male / Middle aged Idioma: En Revista: Clin Biochem Año: 2009 Tipo del documento: Article País de afiliación: Francia Pais de publicación: Estados Unidos

Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Precursores de Proteínas / Fluoroinmunoensayo / Adrenomedulina Límite: Adult / Female / Humans / Male / Middle aged Idioma: En Revista: Clin Biochem Año: 2009 Tipo del documento: Article País de afiliación: Francia Pais de publicación: Estados Unidos