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Change in blood pressure just after initiation of cardiac resynchronization therapy predicts long-term clinical outcome in patients with advanced heart failure.
Tanaka, Yasuaki; Tada, Hiroshi; Yamashita, Eiji; Sato, Chizuru; Irie, Tadanobu; Hori, Yasuhiko; Goto, Koji; Iwamoto, Jotaro; Manni, Hiroki; Yokokawa, Miki; Naito, Shigeto; Oshima, Shigeru; Taniguchi, Koichi.
Afiliación
  • Tanaka Y; Division of Cardiology, Gunma Prefectural Cardiovascular Center, Maebashi, Japan.
Circ J ; 73(2): 288-94, 2009 Feb.
Article en En | MEDLINE | ID: mdl-19110507
BACKGROUND: The aim of this study was to retrospectively investigate the long-term effect of cardiac resynchronization therapy (CRT) and to clarify the useful predictors of clinical outcome. Methods and Results The study group comprised 43 patients with advanced heart failure who underwent CRT (10 females; 66+/-10 years): 23 were in sinus rhythm (SR group) and 20 had chronic atrial fibrillation (AF group). The clinical parameters and echocardiographic data were evaluated before and after CRT. There were no significant differences in the clinical parameters, echocardiographic data at baseline or frequency of responders between the 2 groups. In both groups, the clinical characteristics at baseline did not differ between the responders and non-responders. A prompt rise in systolic blood pressure (SBP) just after CRT was observed more often in responders than in non-responders, and SBP rise > or =5 mmHg was the only significant independent predictor of a CRT responder (P=0.0033). Furthermore, there was a significant difference in the event-free survival between patients with and without SBP rise > or =5 mmHg, demonstrated by Kaplan-Meier method, at 2 years of follow-up (P=0.045). Conclusion A prompt BP rise just after CRT may predict short- and long-term clinical improvement in CRT recipients.
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Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Índice de Severidad de la Enfermedad / Presión Sanguínea / Desfibriladores Implantables / Insuficiencia Cardíaca Tipo de estudio: Diagnostic_studies / Observational_studies / Prognostic_studies / Risk_factors_studies Límite: Aged / Female / Humans / Male / Middle aged Idioma: En Revista: Circ J Asunto de la revista: ANGIOLOGIA / CARDIOLOGIA Año: 2009 Tipo del documento: Article País de afiliación: Japón Pais de publicación: Japón
Buscar en Google
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Imprimir
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PubMed Links

Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Índice de Severidad de la Enfermedad / Presión Sanguínea / Desfibriladores Implantables / Insuficiencia Cardíaca Tipo de estudio: Diagnostic_studies / Observational_studies / Prognostic_studies / Risk_factors_studies Límite: Aged / Female / Humans / Male / Middle aged Idioma: En Revista: Circ J Asunto de la revista: ANGIOLOGIA / CARDIOLOGIA Año: 2009 Tipo del documento: Article País de afiliación: Japón Pais de publicación: Japón