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Fetal and neonatal habituation in infants of diabetic mothers.
Gonzalez-Gonzalez, N L; Medina, V; Padron, E; Domenech, E; Diaz Gomez, N M; Armas, H; Bartha, J L.
Afiliación
  • Gonzalez-Gonzalez NL; Department of Obstetrics and Gynecology, University Hospital of the Canary Islands, Tenerife, Canary Islands, Spain. ngonzalezg@sego.es
J Pediatr ; 154(4): 492-7, 2009 Apr.
Article en En | MEDLINE | ID: mdl-19054526
OBJECTIVE: To evaluate whether maternal diabetes alters the habituation ability of fetuses and newborns. STUDY DESIGN: Two nonrandomized clinical trials were performed. First, we studied prenatal fetuses of women with pregestational diabetes, and control subjects matched for gestational age, and then we studied infants of diabetic mothers (IDM) and control subjects matched for gestational age and mode of delivery. Fetus and newborns were stimulated with vibroacoustic stimulus. RESULTS: In fetuses of diabetic mothers, the ability to habituate was lower, and the habituation rate was higher than in control subjects to all habituation tests. In the neonatal period, ability to habituate was lower (59% vs 100%; P< .001), and the habituation rate was higher (18 [14-21] vs 4 [1.2-6.8]; P< .001) in the IDM than in the control infants. We found a significant negative correlation between maternal glycosylated hemoglobin in each trimester of pregnancy and habituation ability in IDM. CONCLUSIONS: Fetuses and infants of diabetic mothers have impaired habituation ability, which is related to the degree of maternal metabolic control.
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Embarazo en Diabéticas / Recién Nacido / Sistema Nervioso Central / Hijo de Padres Discapacitados / Feto / Habituación Psicofisiológica Tipo de estudio: Clinical_trials Límite: Adult / Female / Humans / Pregnancy País/Región como asunto: Europa Idioma: En Revista: J Pediatr Año: 2009 Tipo del documento: Article País de afiliación: España Pais de publicación: Estados Unidos
Texto completo
Añadir a Mi BVS
Imprimir
XML
PubMed Links
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Embarazo en Diabéticas / Recién Nacido / Sistema Nervioso Central / Hijo de Padres Discapacitados / Feto / Habituación Psicofisiológica Tipo de estudio: Clinical_trials Límite: Adult / Female / Humans / Pregnancy País/Región como asunto: Europa Idioma: En Revista: J Pediatr Año: 2009 Tipo del documento: Article País de afiliación: España Pais de publicación: Estados Unidos