Reduced serotonergic functioning changes heart rate in ADHD.
J Neural Transm (Vienna)
; 116(1): 105-8, 2009 Jan.
Article
en En
| MEDLINE
| ID: mdl-19018449
Reduced mean heart rate (HR) was shown to be a biophysiological marker for aggression, which in turn was proven to be related to changed serotonergic neurotransmission. A total of 16 ADHD-diagnosed boys were subjected to rapid tryptophan depletion (RTD) and a placebo in a double-blind within-subject crossover-design. Mean HR was assessed under RTD/placebo. Low impulsive patients behaving aggressively under RTD showed a lowered HR under RTD versus placebo. Diminished 5-HT functioning was associated with lowered HR and aggressive behaviour.
Texto completo:
1
Colección:
01-internacional
Base de datos:
MEDLINE
Asunto principal:
Trastorno por Déficit de Atención con Hiperactividad
/
Triptófano
/
Serotonina
/
Frecuencia Cardíaca
Tipo de estudio:
Clinical_trials
/
Observational_studies
/
Risk_factors_studies
Límite:
Adolescent
/
Child
/
Humans
/
Male
Idioma:
En
Revista:
J Neural Transm (Vienna)
Año:
2009
Tipo del documento:
Article
País de afiliación:
Alemania
Pais de publicación:
Austria