Alterations of the myenteric plexus of the ileum and the descending colon caused by Toxoplasma gondii (genotype III).
Arq Neuropsiquiatr
; 66(3A): 516-23, 2008 Sep.
Article
en En
| MEDLINE
| ID: mdl-18813711
Alterations caused by a genotype III strain of Toxoplasma gondii were assessed with respect to the number and the morphometry of the myenteric neurons in the terminal ileum and the descending colon. Eighteen rats were divided into four groups: Acute Control Group (ACG, n=4); Acute Experimental Group (AEG, n=4); Chronic Control Group (CCG, n=5) and Chronic Experimental Group (CEG, n=5). NaCl solution was administered through gavage to the animals in the ACG and CCG. Toxoplasma gondii tachyzoites (10(4)) from a genotype III strain were orally administered to the AEG and CEG. Acute Groups were died after 24 hours, and the Chronic Groups after 30 days. Neuronal loss was not observed in both organs. The neurons atrophied in the terminal ileum as the opposite occurred with the neurons at the descending colon during the chronic phase of infection. In the terminal ileum, the neurons atrophied during the chronic phase of the infection as no alteration was found during the acute phase. For the descending colon, the neurons became hypertrophic during the chronic infection in opposition to the atrophy found during the acute phase.
Texto completo:
1
Colección:
01-internacional
Base de datos:
MEDLINE
Asunto principal:
Sistema Nervioso Autónomo
/
Toxoplasma
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Toxoplasmosis Animal
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Íleon
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Parasitosis Intestinales
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Plexo Mientérico
Límite:
Animals
Idioma:
En
Revista:
Arq Neuropsiquiatr
Año:
2008
Tipo del documento:
Article
País de afiliación:
Brasil
Pais de publicación:
Alemania