Your browser doesn't support javascript.
loading
Early microbiological response to linezolid vs vancomycin in ventilator-associated pneumonia due to methicillin-resistant Staphylococcus aureus.
Wunderink, Richard G; Mendelson, Meryl H; Somero, Michael S; Fabian, Timothy C; May, Addison K; Bhattacharyya, Helen; Leeper, Kenneth V; Solomkin, Joseph S.
Afiliación
  • Wunderink RG; Northwestern University, Chicago, IL. Electronic address: r-wunderink@northwestern.edu.
  • Mendelson MH; Pfizer Inc, New York, NY.
  • Somero MS; Desert Regional Medical Center, Palm Springs, CA.
  • Fabian TC; University of Tennessee, Memphis, TN.
  • May AK; Vanderbilt University, Nashville, TN.
  • Bhattacharyya H; Pfizer Inc, New York, NY.
  • Leeper KV; Emory University, Atlanta, GA.
  • Solomkin JS; University of Cincinnati College of Medicine, Cincinnati, OH.
Chest ; 134(6): 1200-1207, 2008 Dec.
Article en En | MEDLINE | ID: mdl-18719064
BACKGROUND: Methicillin-resistant Staphylococcus aureus (MRSA) is a common cause of ventilator-associated pneumonia (VAP). This prospective, open-label, multicenter clinical trial compared the early microbiological efficacy of linezolid (LZD) therapy with that of vancomycin (VAN) therapy in patients with MRSA VAP. METHODS: A total of 149 patients with suspected MRSA VAP were randomized to receive either LZD, 600 mg, or VAN, 1 g every 12 h. Patients with baseline bronchoscopic BAL (BBAL) fluid quantitative culture findings that were positive for MRSA (>or= 10(4) cfu/mL) comprised the study population. The primary outcome was microbiological response (
Asunto(s)
Texto completo
Añadir a Mi BVS
Imprimir
XML
PubMed Links
Buscar en Google

Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Infecciones Estafilocócicas / Vancomicina / Oxazolidinonas / Neumonía Asociada al Ventilador / Staphylococcus aureus Resistente a Meticilina / Acetamidas / Antibacterianos Tipo de estudio: Clinical_trials / Diagnostic_studies / Observational_studies / Prognostic_studies / Risk_factors_studies Límite: Adult / Aged / Female / Humans / Male / Middle aged Idioma: En Revista: Chest Año: 2008 Tipo del documento: Article Pais de publicación: Estados Unidos
Texto completo
Añadir a Mi BVS
Imprimir
XML
PubMed Links
Buscar en Google

Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Infecciones Estafilocócicas / Vancomicina / Oxazolidinonas / Neumonía Asociada al Ventilador / Staphylococcus aureus Resistente a Meticilina / Acetamidas / Antibacterianos Tipo de estudio: Clinical_trials / Diagnostic_studies / Observational_studies / Prognostic_studies / Risk_factors_studies Límite: Adult / Aged / Female / Humans / Male / Middle aged Idioma: En Revista: Chest Año: 2008 Tipo del documento: Article Pais de publicación: Estados Unidos