Etiopathogenesis of osteoarthritis.
Rheum Dis Clin North Am
; 34(3): 531-59, 2008 Aug.
Article
en En
| MEDLINE
| ID: mdl-18687271
In this article, the authors posit that, because osteoarthritis (OA) involves all of the tissues of the synovial joint, the emphasis on the loss of cartilage, in particular, is misguided. In contrast, the authors view OA as a process that is attempting to contain a mechanical problem in the joint. They argue that OA is best defined as failed repair of damage that has been caused by excessive mechanical stress on joint tissues. Because the body's innate mechanisms for repairing the damaged tissues cannot be effective in the face of the overwhelming mechanical abnormality, they cannot solve the problem of OA.
Texto completo:
1
Colección:
01-internacional
Base de datos:
MEDLINE
Asunto principal:
Osteoartritis
/
Dolor
Tipo de estudio:
Etiology_studies
/
Observational_studies
/
Prognostic_studies
/
Risk_factors_studies
Límite:
Female
/
Humans
/
Male
Idioma:
En
Revista:
Rheum Dis Clin North Am
Asunto de la revista:
REUMATOLOGIA
Año:
2008
Tipo del documento:
Article
País de afiliación:
Estados Unidos
Pais de publicación:
Estados Unidos