Carbon nanotubes in macrophages: imaging and chemical analysis by X-ray fluorescence microscopy.

Bussy, Cyrill; Cambedouzou, Julien; Lanone, Sophie; Leccia, Emilie; Heresanu, Vasile; Pinault, Mathieu; Mayne-L'hermite, Martine; Brun, Nathalie; Mory, Claudie; Cotte, Marine; Doucet, Jean; Boczkowski, Jorge; Launois, Pascale

Bussy, Cyrill; Cambedouzou, Julien; Lanone, Sophie; Leccia, Emilie; Heresanu, Vasile; Pinault, Mathieu; Mayne-L'hermite, Martine; Brun, Nathalie; Mory, Claudie; Cotte, Marine; Doucet, Jean; Boczkowski, Jorge; Launois, Pascale.

Afiliación

Bussy C; Laboratoire de Physique des Solides, UMR 8502 CNRS, Universite Paris Sud, Bat. 510, Orsay F-91405, France. bussy@lps.u-psud.fr

Nano Lett ; 8(9): 2659-63, 2008 Sep.

Article en En | MEDLINE | ID: mdl-18672943

RESUMEN

X-ray fluorescence microscopy (microXRF) is applied for the first time to study macrophages exposed to unpurified and purified single-walled (SW) and multiwalled (MW) carbon nanotubes (CNT). Investigating chemical elemental distributions allows one to (i) image nanotube localization within a cell and (ii) detect chemical modification of the cell after CNT internalization. An excess of calcium is detected for cells exposed to unpurified SWCNT and MWCNT and related toxicological assays are discussed.

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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Idioma: En Revista: Nano Lett Año: 2008 Tipo del documento: Article País de afiliación: Francia Pais de publicación: Estados Unidos

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