Separation of [Sp]-3'-O-(5'-dimethoxytritylthymidyl)-5'-O-(3'camphanoyl thymidyl)-O-methyl phosphite.
Nucleic Acids Symp Ser
; (24): 63-6, 1991.
Article
en En
| MEDLINE
| ID: mdl-1841382
First isolation of diastereoisomerically enriched (d.p. 95%) [Sp]-3'-O-(5'-dimethoxytrityl tjymidyl)-5'-O-(3'-camphanoyl thymidyl)-O-methyl phosphite (1) allowed to assign, via sulfuration and deprotection, its absolute configuration as Sp. Its reactions with methyl iodide, dimethoxytrityl chloride, or water, respectively, allowed to confirm correctness of assignment of absolute configuration in diastereisomers of TPMeT, and to assign absolute configuration in corresponding diastereoisomers of TPDMTT and TPHT.
Buscar en Google
Colección:
01-internacional
Base de datos:
MEDLINE
Asunto principal:
Timidina
/
Fosfitos
Idioma:
En
Revista:
Nucleic Acids Symp Ser
Año:
1991
Tipo del documento:
Article
Pais de publicación:
Reino Unido