Brain perfusion abnormalities in a sibship with parkin-linked parkinsonism.
Parkinsonism Relat Disord
; 14(7): 581-3, 2008 Nov.
Article
en En
| MEDLINE
| ID: mdl-18331811
We demonstrated brain perfusion abnormalities in a sibship with parkin-linked parkinsonism. The sibship consisted of a 64-year-old man and a 62-year-old woman. Both patients had homozygous deletions of exon 4 in the parkin gene. Hypoperfusion in the superior and middle frontal gyrus, and head of caudate nucleus was seen by SPECT with easy Z score imaging system in both patients. These findings may reflect their executive dysfunction demonstrated by neuropsychological tests.
Texto completo:
1
Colección:
01-internacional
Base de datos:
MEDLINE
Asunto principal:
Encéfalo
/
Trastornos Parkinsonianos
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Hermanos
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Ubiquitina-Proteína Ligasas
Límite:
Female
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Humans
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Male
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Middle aged
Idioma:
En
Revista:
Parkinsonism Relat Disord
Asunto de la revista:
NEUROLOGIA
Año:
2008
Tipo del documento:
Article
País de afiliación:
Japón
Pais de publicación:
Reino Unido