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Recovery of visual functions after early acquired occipital damage.
Bova, S M; Giovenzana, A; Signorini, S; La Piana, R; Uggetti, C; Bianchi, P E; Fazzi, E.
Afiliación
  • Bova SM; Centre of Child Neuro-Ophthalmology, Department of Child Neurology and Psychiatry, University of Pavia, Italy. stefania.bova@icp.mi.it
Dev Med Child Neurol ; 50(4): 311-5, 2008 Apr.
Article en En | MEDLINE | ID: mdl-18312600
Plasticity of visual systems after early brain damage has been extensively studied in animal models but poorly documented in children after visual pathway lesions. This report describes the visual recovery of a male child who had a bilateral occipital lobe infarction at the age of 2 years 6 months, 10 days after colon resection for Hirschsprung disease. In the acute phase he had severe visual impairment without visual response. Some weeks later he could perceive movement. Since then, progressive recovery of his visual acuity and oculomotor abilities has been accompanied by a progressive reduction of the visual field defect. At 6 years 8 months, visual recognition acuity was 10/10 in both eyes and neuro-ophthalmological examination was normal, except for persistence of the visual field defect in the upper hemifield and a selective impairment of higher visual functions (recognition of object presented in a hard-to-decode way [e.g. overlapping figures], or use of complex visuospatial skills). The functional recovery observed in this patient confirms the adaptive plasticity of developing visual systems after early brain lesions. It suggests that in humans, as in animal models, processes related to cerebral plasticity may take place years after a brain lesion has been sustained.
Asunto(s)

Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Complicaciones Posoperatorias / Imagen por Resonancia Magnética / Ceguera / Infarto de la Arteria Cerebral Posterior / Plasticidad Neuronal / Lóbulo Occipital Tipo de estudio: Diagnostic_studies / Observational_studies / Prognostic_studies / Risk_factors_studies Límite: Child / Child, preschool / Female / Humans / Male Idioma: En Revista: Dev Med Child Neurol Año: 2008 Tipo del documento: Article País de afiliación: Italia Pais de publicación: Reino Unido

Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Complicaciones Posoperatorias / Imagen por Resonancia Magnética / Ceguera / Infarto de la Arteria Cerebral Posterior / Plasticidad Neuronal / Lóbulo Occipital Tipo de estudio: Diagnostic_studies / Observational_studies / Prognostic_studies / Risk_factors_studies Límite: Child / Child, preschool / Female / Humans / Male Idioma: En Revista: Dev Med Child Neurol Año: 2008 Tipo del documento: Article País de afiliación: Italia Pais de publicación: Reino Unido