Biofunctionalized lipid-polymer hybrid nanocontainers with controlled permeability.
Nano Lett
; 8(4): 1105-10, 2008 Apr.
Article
en En
| MEDLINE
| ID: mdl-18311934
We have successfully developed, for the first time, a novel polymer-lipid hybrid nanocontainer with controlled permeability functionality. The nanocontainer is made by nanofabricating holes with desired dimensions in an impermeable polymer scaffold by focused ion beam drilling and sealing them with lipid bilayers containing remote-controlled pore-forming channel proteins. This system allows exchange of solutions only after channel activation at will to form temporary pores in the container. Potential applications are foreseen in bionanosensors, nanoreactors, nanomedicine, and triggered delivery.
Texto completo:
1
Colección:
01-internacional
Base de datos:
MEDLINE
Asunto principal:
Polímeros
/
Nanoestructuras
/
Lípidos
Idioma:
En
Revista:
Nano Lett
Año:
2008
Tipo del documento:
Article
País de afiliación:
Países Bajos
Pais de publicación:
Estados Unidos