Detection of Philadelphia chromosome in patients with chronic myeloid leukemia from the Presov region in Slovakia (1995-2004).
Bratisl Lek Listy
; 108(10-11): 433-6, 2007.
Article
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| MEDLINE
| ID: mdl-18306721
Philadelphia chromosome (Ph) is a characteristic chromosomal marker that is associated with chronic myelogenous leukemia (CML). Philadelphia chromosome in bone marrow cells in patients with suspected diagnosis of CML in the Presov region (1995-2004) was detected in 94.4 % of cases. In one patient a complex translocation involving the chromosomes 8, 9 and 22 was identified. One patient has showed extra numerical and structural chromosomal aberrations. The mosaic karyotype of Ph chromosome was found in 5.9 % of cases. The conventional cytogenetic analysis remains the standard method for the purpose of diagnosis and monitoring of the therapeutic response and minimal residual disease in patients with chronic myeloid leukemia (Tab. 1, Fig. 1, Ref. 18). Full Text (Free, PDF) www.bmj.sk.
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Colección:
01-internacional
Base de datos:
MEDLINE
Asunto principal:
Cromosoma Filadelfia
/
Leucemia Mielógena Crónica BCR-ABL Positiva
Tipo de estudio:
Diagnostic_studies
/
Prognostic_studies
Límite:
Adult
/
Aged
/
Humans
/
Middle aged
País/Región como asunto:
Europa
Idioma:
En
Revista:
Bratisl Lek Listy
Año:
2007
Tipo del documento:
Article
País de afiliación:
Eslovaquia
Pais de publicación:
Eslovaquia