Etiology of sperm immunity in women.
Fertil Steril
; 91(2): 639-43, 2009 Feb.
Article
en En
| MEDLINE
| ID: mdl-18281044
Sperm immunity in females can reduce the likelihood of natural conception, and sperm antibodies from female sera have been shown to inhibit IVF in humans and in several animal models. The etiology of sperm immunity in human females is unknown, but several possible mechanisms have been proposed, including cross-reactivity with microbial antigens and interferon gamma-mediated potentiation of the antisperm immune response in women whose male partners have sperm autoantibodies in their semen. This article reviews these ideas and postulates a novel hypothesis based on the potential for the generation of anti-idiotype antibodies in women whose partners have sperm antibodies in their semen.
Texto completo:
1
Colección:
01-internacional
Base de datos:
MEDLINE
Asunto principal:
Semen
/
Espermatozoides
/
Idiotipos de Inmunoglobulinas
/
Infertilidad Femenina
/
Anticuerpos
Tipo de estudio:
Etiology_studies
/
Prognostic_studies
/
Risk_factors_studies
Límite:
Female
/
Humans
/
Male
Idioma:
En
Revista:
Fertil Steril
Año:
2009
Tipo del documento:
Article
País de afiliación:
Australia
Pais de publicación:
Estados Unidos