Methadone induced torsade de pointes in a patient receiving antiretroviral therapy.
Ir Med J
; 100(10): 631-2, 2007.
Article
en En
| MEDLINE
| ID: mdl-18277734
Adverse drug reactions account for approximately 5% of acute medical admissions. A 34-year-old male patient receiving antiretroviral therapy, methadone and flurazepam presented to the emergency room following collapse with associated loss of consciousness. Cardiac monitoring demonstrated marked Q-T prolongation followed by the cardiac arrhythmia, torsade de pointes. The patient made a full recovery following withdrawal of the antiretroviral therapy and a reduction in methadone dose. Methadone is a recognised cause of this potentially fatal cardiac arrhythmia which is more likely to occur when methadone metabolism is inhibited by drugs such as HIV tease inhibitors.
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Colección:
01-internacional
Base de datos:
MEDLINE
Asunto principal:
Torsades de Pointes
/
Antirretrovirales
/
Metadona
/
Narcóticos
Límite:
Adult
/
Humans
/
Male
Idioma:
En
Revista:
Ir Med J
Año:
2007
Tipo del documento:
Article
Pais de publicación:
Irlanda