Effects of carovertin on the reaction of retinal pigmented epithelium and radial glia to bright light.

Logvinov, S V; Plotnikov, M B; Varakuta, E Yu; Zhdankina, A A; Potapov, A V; Mikhulya, E P

Logvinov, S V; Plotnikov, M B; Varakuta, E Yu; Zhdankina, A A; Potapov, A V; Mikhulya, E P.

Afiliación

Logvinov SV; Department of Histology, Embryology, and Cytology, Siberian State Medical University, Tomsk. s_logvinov@mail.ru

Bull Exp Biol Med ; 144(1): 100-2, 2007 Jul.

Article en En, Ru | MEDLINE | ID: mdl-18256765

RESUMEN

Light exposure (6000 lux, 6 h) caused reactive changes in rat retinal pigmented epithelium and radial glia on day 1. Foci of lesions with virtually complete absence of the layers formed by neurosensory cells appeared on day 7. The number of destructively changed radial gliocytes in these foci was by one order of magnitude higher than in the control. Carovertin reduced destruction of pigmented epithelium and radial glia and reduced the area of lesion foci.

Asunto(s)

Ácido Ascórbico/farmacología; Luz/efectos adversos; Neuroglía/efectos de los fármacos; Neuroglía/efectos de la radiación; Epitelio Pigmentado Ocular/efectos de los fármacos; Epitelio Pigmentado Ocular/efectos de la radiación; Quercetina/análogos & derivados; beta Caroteno/farmacología; Animales; Flavonoles/farmacología; Masculino; Quercetina/farmacología; Ratas

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Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Epitelio Pigmentado Ocular / Ácido Ascórbico / Quercetina / Neuroglía / Beta Caroteno / Luz Límite: Animals Idioma: En / Ru Revista: Bull Exp Biol Med Año: 2007 Tipo del documento: Article Pais de publicación: Estados Unidos

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