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A DMPA Langmuir monolayer study: from gas to solid phase. An atomistic description by molecular dynamics Simulation.
Giner-Casares, J J; Camacho, L; Martín-Romero, M T; Cascales, J J López.
Afiliación
  • Giner-Casares JJ; Universidad de Córdoba, Dpto. Química Física y TermodinAmica Aplicada, Ed. Marie Curie, Campus de Rabanales, 14014 Córdoba, Spain.
Langmuir ; 24(5): 1823-8, 2008 Mar 04.
Article en En | MEDLINE | ID: mdl-18225932
In this work, a DMPA Langmuir monolayer at the air/water interface was studied by molecular dynamics simulations. Thus, an atomistic picture of a Langmuir monolayer was drawn from its expanded gas phase to its final solid condensed one. In this sense, some properties of monolayers that were traditionally poorly or even not reproduced in computer simulations, such as lipid domain formation or pressure-area per lipid isotherm, were properly reproduced in this work. Thus, the physical laws that control the lipid domain formation in the gas phase and the structure of lipid monolayers from the gas to solid condensed phase were studied. Thanks to the atomistic information provided by the molecular dynamics simulations, we were able to add valuable information to the experimental description of these processes and to access experimental data related to the lipid monolayers in their expanded phase, which is difficult or inaccessible to study by experimental techniques. In this sense, properties such as lipids head hydration and lipid structure were studied.
Asunto(s)

Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Simulación por Computador / Agua / Compuestos de Anilina / Modelos Químicos Idioma: En Revista: Langmuir Asunto de la revista: QUIMICA Año: 2008 Tipo del documento: Article País de afiliación: España Pais de publicación: Estados Unidos

Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Simulación por Computador / Agua / Compuestos de Anilina / Modelos Químicos Idioma: En Revista: Langmuir Asunto de la revista: QUIMICA Año: 2008 Tipo del documento: Article País de afiliación: España Pais de publicación: Estados Unidos