Lycopene in cancer prevention and treatment.

Seren, Soley; Lieberman, Ronald; Bayraktar, Ulas D; Heath, Elisabeth; Sahin, Kazim; Andic, Fundagul; Kucuk, Omer

Seren, Soley; Lieberman, Ronald; Bayraktar, Ulas D; Heath, Elisabeth; Sahin, Kazim; Andic, Fundagul; Kucuk, Omer.

Afiliación

Seren S; Department of Internal Medicine, Wayne State University, Barbara Ann Karmanos Cancer Institute, Detroit, Michigan 48201, USA.

Am J Ther ; 15(1): 66-81, 2008.

Article en En | MEDLINE | ID: mdl-18223356

RESUMEN

Dietary intake of lycopene is inversely associated with the risk of many cancers. Preclinical studies show that lycopene has potent in vitro and in vivo antitumor effects, suggesting potential preventive and therapeutic roles for the compound. However, clinical trials with lycopene have only recently been started, and available clinical data preclude firm conclusions with regard to its use in cancer prevention and treatment. Further mechanistic studies and randomized controlled clinical intervention trials with lycopene involving cancer patients are warranted.

Asunto(s)

Anticarcinógenos/farmacología; Carotenoides/farmacología; Neoplasias/tratamiento farmacológico; Animales; Anticarcinógenos/uso terapéutico; Carotenoides/uso terapéutico; Ensayos Clínicos como Asunto; Dieta; Evaluación Preclínica de Medicamentos; Humanos; Licopeno; Neoplasias/prevención & control

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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Carotenoides / Anticarcinógenos / Neoplasias Tipo de estudio: Clinical_trials Límite: Animals / Humans Idioma: En Revista: Am J Ther Asunto de la revista: TERAPEUTICA Año: 2008 Tipo del documento: Article País de afiliación: Estados Unidos Pais de publicación: Estados Unidos

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