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The importance of using multiple techniques for detection of platelet antibodies.
Smith, G A; Ranasinghe, E; Ouwehand, W H.
Afiliación
  • Smith GA; Platelet Immunology Reference Laboratory, National Health Service Blood and Transplant, Cambridge, UK.
Vox Sang ; 93(4): 306-8, 2007 Nov.
Article en En | MEDLINE | ID: mdl-18070274
In red cell immunology, it has long been known that no one technique will detect all clinically significant antibodies. The same appears to be true for platelet immunology, and we highlight this fact by showing four examples of anti-human platelet antigen-1a that were not detected by the monoclonal antibody-specific immobilization of platelet antigen test, the most commonly used technique. Each antibody was found in a case of fetomaternal alloimmune thrombocytopenia in which the fetus or neonate was severely affected.
Asunto(s)
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Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Plaquetas / Inmunoensayo / Antígenos de Plaqueta Humana / Trombocitopenia Neonatal Aloinmune / Isoanticuerpos Tipo de estudio: Diagnostic_studies Límite: Female / Humans / Pregnancy Idioma: En Revista: Vox Sang Año: 2007 Tipo del documento: Article Pais de publicación: Reino Unido
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Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Plaquetas / Inmunoensayo / Antígenos de Plaqueta Humana / Trombocitopenia Neonatal Aloinmune / Isoanticuerpos Tipo de estudio: Diagnostic_studies Límite: Female / Humans / Pregnancy Idioma: En Revista: Vox Sang Año: 2007 Tipo del documento: Article Pais de publicación: Reino Unido