Interferometric phase-dispersion microscopy.

Yang, C; Wax, A; Georgakoudi, I; Hanlon, E B; Badizadegan, K; Dasari, R R; Feld, M S

Yang, C; Wax, A; Georgakoudi, I; Hanlon, E B; Badizadegan, K; Dasari, R R; Feld, M S.

Afiliación

Yang C; George Harrison Spectroscopy Laboratory, Massachusetts Institute of Technology, Cambridge, Massachusetts 02139, USA.

Opt Lett ; 25(20): 1526-8, 2000 Oct 15.

Article en En | MEDLINE | ID: mdl-18066267

RESUMEN

We describe a new scanning microscopy technique, phase-dispersion microscopy (PDM). The technique is based on measuring the phase difference between the fundamental and the second-harmonic light in a novel interferometer. PDM is highly sensitive to subtle refractive-index differences that are due to dispersion (differential optical path sensitivity, 5 nm). We apply PDM to measure minute amounts of DNA in solution and to study biological tissue sections. We demonstrate that PDM performs better than conventional phase-contrast microscopy in imaging dispersive and weakly scattering samples.

Buscar en Google

Añadir a Mi BVS

Imprimir

XML

PubMed Links

Colección: 01-internacional Base de datos: MEDLINE Idioma: En Revista: Opt Lett Año: 2000 Tipo del documento: Article País de afiliación: Estados Unidos Pais de publicación: Estados Unidos

Buscar en Google

Añadir a Mi BVS

Imprimir

XML

PubMed Links