State of the art and recent advance in the treatment of resectable nonmetastatic rectal cancer.

Ortholan, C; Gerard, J P; Benezery, K; Francois, E

Ortholan, C; Gerard, J P; Benezery, K; Francois, E.

Afiliación

Ortholan C; Centre Antoine-Lacassagne, NICE, 33 Avenue de Valombrose, 06189 NICE Cedex, France.

Surg Oncol ; 16 Suppl 1: S125-8, 2007 Dec.

Article en En | MEDLINE | ID: mdl-18023572

RESUMEN

INTRODUCTION: Standard treatment is achieving good local control for rectal cancer. Innovative approach is aiming at increasing conservative treatment. METHODOLOGY: Strong evidence relies on randomized trials. Phase I and II trials are the method to evaluate advances. RESULTS: Preoperative radiotherapy with concurrent chemotherapy is the standard treatment for most of the T3 (4) tumors. To increase conservative treatment innovative neoadjuvant treatment achieving complete clinical response is a promising approach. CONCLUSION: Well-conducted clinical trials are improving the standard treatments and are evaluating new hypotheses.

Asunto(s)

Neoplasias del Recto/terapia; Ensayos Clínicos como Asunto; Humanos; Terapia Neoadyuvante

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Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Neoplasias del Recto Tipo de estudio: Clinical_trials Límite: Humans Idioma: En Revista: Surg Oncol Asunto de la revista: NEOPLASIAS Año: 2007 Tipo del documento: Article País de afiliación: Francia Pais de publicación: Países Bajos

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