[Determination of nystatin component composition using HPLC and TLC with densitometry]. / Opredelenie komponentnogo sostava nistatina metodami VEZhKh i TSKh s ispol'zovaniem densitometrii.
Antibiot Khimioter
; 36(11): 9-11, 1991 Nov.
Article
en Ru
| MEDLINE
| ID: mdl-1793301
The component composition of nystatin produced by an improved strain of Streptomyces noursei was determined by HPLC on Milichrom chromatograph (USSR). It was shown that the antibiotic consisted of nystatins A1, A2, A3 and B and admixture substances. The data appeared to be in good agreement with the results of the complex TLC investigation, by using densitometry. The component composition of the samples was evidenced by SIEAP mass spectrometry. Physiochemical and biological characteristics of separate components are presented.
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Colección:
01-internacional
Base de datos:
MEDLINE
Asunto principal:
Nistatina
Idioma:
Ru
Revista:
Antibiot Khimioter
Asunto de la revista:
TERAPIA POR MEDICAMENTOS
Año:
1991
Tipo del documento:
Article
Pais de publicación:
Rusia