ABO-incompatible pediatric bone marrow transplantation: a simple method to remove red blood cells from small volume marrow grafts.
Bone Marrow Transplant
; 8(6): 473-6, 1991 Dec.
Article
en En
| MEDLINE
| ID: mdl-1790427
A simple and reliable technique for removal of ABO incompatible marrow red cells is described. This method requires a blood cell processor and third party red cells are used as a shelf. Using this technique, nine children age 0.5-11.5 years received allogeneic bone marrow transplantation from ABO incompatible donors. A median of 4.8 ml of incompatible red cells were transfused. There was no evidence of a hemolytic transfusion reaction in any patient. A median of 75% of nucleated marrow cells were recovered and used for transplantation. Engraftment occurred at the same time as with ABO compatible transplants. Autologous marrow red cells were reinfused into four young donors. This 'shelf' technique for red cell depletion is an acceptable method for processing small volume, ABO incompatible marrow harvests from pediatric donors.
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Colección:
01-internacional
Base de datos:
MEDLINE
Asunto principal:
Sistema del Grupo Sanguíneo ABO
/
Células de la Médula Ósea
/
Separación Celular
/
Trasplante de Médula Ósea
/
Eritrocitos
Límite:
Child
/
Child, preschool
/
Humans
/
Infant
Idioma:
En
Revista:
Bone Marrow Transplant
Asunto de la revista:
TRANSPLANTE
Año:
1991
Tipo del documento:
Article
País de afiliación:
Canadá
Pais de publicación:
Reino Unido