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Electrocardiographic characteristics in a population with high rates of seropositivity for Trypanosoma cruzi infection.
Williams-Blangero, S; Magalhaes, T; Rainwater, E; Blangero, J; Corrêa-Oliveira, R; Vandeberg, J L.
Afiliación
  • Williams-Blangero S; Department of Genetics, Southwest Foundation for Biomedical Research, San Antonio, Texas, USA. sarah@darwin.sfbr.org
Am J Trop Med Hyg ; 77(3): 495-9, 2007 Sep.
Article en En | MEDLINE | ID: mdl-17827366
This study was conducted in Posse, a rural community in Goiàs, Brazil. Persons were recruited into the study through house-to-house sampling of all houses in the sampled area. Blood samples were collected for seropositivity assessments for Trypanosoma cruzi and an electrocardiogram was assessed using a portable system. The results demonstrate significant differences between seropositive and seronegative persons for electrocardiographic (ECG)-derived traits. Seropositive persons had substantially longer QRS and QT intervals than seronegative persons. The PR interval was significantly different between seropositive and seronegative persons. Conduction abnormalities were observed more frequently in seropositive than seronegative persons. Right bundle branch block, an ECG abnormality typical of Chagas disease, was observed in 15% of seropositive persons compared with less than 1% of seronegative persons. Results indicate that T. cruzi infection and subsequent Chagas disease will continue to be major health problems for the foreseeable future in this typical rural area of Brazil.
Asunto(s)
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Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Enfermedad de Chagas / Cardiopatías Límite: Animals / Female / Humans / Male País/Región como asunto: America do sul / Brasil Idioma: En Revista: Am J Trop Med Hyg Año: 2007 Tipo del documento: Article País de afiliación: Estados Unidos Pais de publicación: Estados Unidos
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Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Enfermedad de Chagas / Cardiopatías Límite: Animals / Female / Humans / Male País/Región como asunto: America do sul / Brasil Idioma: En Revista: Am J Trop Med Hyg Año: 2007 Tipo del documento: Article País de afiliación: Estados Unidos Pais de publicación: Estados Unidos