[Hormonal treatment in transsexual patients. Metabolic consequences]. / Le traitement hormonal des patients transsexuels et ses conséquences métaboliques.
Ann Endocrinol (Paris)
; 68(4): 258-64, 2007 Sep.
Article
en Fr
| MEDLINE
| ID: mdl-17693385
Transsexualism is a sexual identity disorder distinguished by the extreme conviction of belonging to the opposite sex with a total disharmony in the original sex. Diagnosis is established when patients respond to three criteria (DSM-IV): 1) Desire to live and to be accepted as members of opposite sex; 2) Presence of sexual identity disorder for minimal two years; 3) Lack of mental disease or chromosomal anomalies. When diagnosis is confirmed, hormonal treatment can be started and so, improve the secondary sexual characters of selected sex. For patients F-M, treatment is composed of testosterone, most commonly esters of testosterone. For patients M-F, treatment consists of estrogens. These estrogens are frequently associated to an anti-androgen (cyproterone acetate) in the pre-reassignment phase. Avoiding the hepatic way, transdermal form is recommended. Hormonal treatments are not devoid of secondary effects: the most frequent one is venous thromboembolism. Considering contraindications and potential complications, each patient must be selected carefully. The endocrinological follow-up is essential and necessary.
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Colección:
01-internacional
Base de datos:
MEDLINE
Asunto principal:
Transexualidad
/
Estrógenos
/
Andrógenos
Tipo de estudio:
Diagnostic_studies
Límite:
Female
/
Humans
/
Male
Idioma:
Fr
Revista:
Ann Endocrinol (Paris)
Año:
2007
Tipo del documento:
Article
País de afiliación:
Bélgica
Pais de publicación:
Francia