[Tumor lysis syndrome]. / Syndrome de lyse tumorale.
Tunis Med
; 85(2): 174-6, 2007 Feb.
Article
en Fr
| MEDLINE
| ID: mdl-17665670
Tumor lysis syndrome is a potentially life threatening oncologic emergency that requires immediate medical intervention. The syndrome results from the destruction (or lysis) of a large number of rapidly dividing malignant cells spontaneously or during chemotherapy. The resulting metabolic abnormalities include hyperkaliemia, hyperuricemia, and hyperphosphatemia with secondary hypocalcemia, all of which put patients at risk for renal failure and alteration in cardiac function. The tumor lysis syndrome occurs most often in patients with large tumor burdens that are very sensitive to chemotherapy and radiotherapy, such as acute or chronic leukaemias with high leukocyte counts and high-grade lymphoma. The current standard management for tumor lysis syndrome consists of allopurinol or recombinant urate oxidase for high risk patient in conjunction with i.v. hydratation with or without alkalinization.
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Colección:
01-internacional
Base de datos:
MEDLINE
Asunto principal:
Síndrome de Lisis Tumoral
Tipo de estudio:
Etiology_studies
Límite:
Humans
Idioma:
Fr
Revista:
Tunis Med
Año:
2007
Tipo del documento:
Article
Pais de publicación:
Túnez