Innate pathogen recognition in the kidney: toll-like receptors, NOD-like receptors, and RIG-like helicases.

Anders, H-J

Anders, H-J.

Afiliación

Anders HJ; Department of Nephrology, Medical Policlinic, University of Munich, Munich, Germany. hjanders@med.uni-muenchen.de

Kidney Int ; 72(9): 1051-6, 2007 Nov.

Article en En | MEDLINE | ID: mdl-17653134

RESUMEN

How do infections trigger or aggravate renal pathology? The discovery of the toll-like receptors, and more recently, the retinoic-acid-inducible protein-like helicases and the nucleotide-binding oligomerization domain-like receptors may offer new concepts to answer this question. Common pathogen-associated molecules are recognized by these receptors in several cellular compartments of immune cells and non-immune cells inside the kidney. This article summarizes ligand-receptor interactions and their known or potential significance in kidney diseases.

Asunto(s)

Inmunidad Innata/fisiología; Enfermedades Renales/inmunología; Humanos; Enfermedades Renales/fisiopatología; Proteínas Adaptadoras de Señalización NOD/fisiología; ARN Helicasas/fisiología; Receptores Toll-Like/fisiología

Buscar en Google

Añadir a Mi BVS

Imprimir

XML

PubMed Links

Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Inmunidad Innata / Enfermedades Renales Límite: Humans Idioma: En Revista: Kidney Int Año: 2007 Tipo del documento: Article País de afiliación: Alemania Pais de publicación: Estados Unidos

Buscar en Google

Añadir a Mi BVS

Imprimir

XML

PubMed Links