PSA reduction (after antibiotics) permits to avoid or postpone prostate biopsy in selected patients.
Prostate Cancer Prostatic Dis
; 11(2): 148-52, 2008.
Article
en En
| MEDLINE
| ID: mdl-17637759
Microscopic foci of prostatitis may induce prostate-specific antigen (PSA) increase. PSA reduction after antibiotics might identify those patients in whom biopsy can be avoided. Ninety-nine patients received ciprofloxacin for 3 weeks, of whom 59 showed PSA reduction. Histology detected small foci of prostatitis in 65% of cases. Carcinoma was found in 40 and 20.3% of patients with unchanged or decreased PSA, respectively (P=0.03). No cancer was detected if PSA decreased below 4 ng/ml or more than 70%. Biopsy can be postponed, with a low risk of missing a cancer, if PSA decreases more than 70% or below 4 ng/ml.
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Colección:
01-internacional
Base de datos:
MEDLINE
Asunto principal:
Próstata
/
Prostatitis
/
Biopsia con Aguja
/
Ciprofloxacina
/
Antígeno Prostático Específico
/
Procedimientos Innecesarios
/
Antibacterianos
Tipo de estudio:
Diagnostic_studies
/
Etiology_studies
/
Observational_studies
/
Prognostic_studies
/
Risk_factors_studies
Límite:
Aged
/
Aged80
/
Humans
/
Male
/
Middle aged
Idioma:
En
Revista:
Prostate Cancer Prostatic Dis
Asunto de la revista:
ENDOCRINOLOGIA
/
NEOPLASIAS
/
UROLOGIA
Año:
2008
Tipo del documento:
Article
País de afiliación:
Italia
Pais de publicación:
Reino Unido