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Case of severe refractory myasthenia gravis in HUKM.
Hamizah, R; Norlinah, M I; Tan, H J; Soehardy, Z; Halim, A G; Rohana, A G; Hamidon, B B; Kong, N C T; Raymond, A A.
Afiliación
  • Hamizah R; Department of Medicine, Hospital UKM, Jalan Yaacob Latiff, Bandar Tun Razak 56000, Kuala Lumpur.
Med J Malaysia ; 61(5): 633-5, 2006 Dec.
Article en En | MEDLINE | ID: mdl-17623968
A 20-year-old girl first notice bilateral ocular muscle weakness in 2001. Two months later, she developed acute muscle paralysis and respiratory failure which required ventilation. Serum anti-acetylcholine receptor antibodies and repetitive nerve stimulation test was positive and consistent with myasthenia gravis (MG). CT scan thorax revealed thymic enlargement and she underwent a video assisted thymectomy (VATS). However, over the next three years, despite maximal doses of various immunosuppressive agents with plasmapheresis and intravenous immunoglobulin, she was admitted with recurrent myasthenic crisis without any obvious precipitant. She was then commenced on mycophenolate mofetil and together with regular plasmapheresis, cyclosporine and prednisolone, her symptoms have finally improved and brought under control.
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Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Timectomía / Inmunoglobulinas / Inmunosupresores / Miastenia Gravis Tipo de estudio: Diagnostic_studies Límite: Adult / Female / Humans Idioma: En Revista: Med J Malaysia Año: 2006 Tipo del documento: Article Pais de publicación: Malasia
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Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Timectomía / Inmunoglobulinas / Inmunosupresores / Miastenia Gravis Tipo de estudio: Diagnostic_studies Límite: Adult / Female / Humans Idioma: En Revista: Med J Malaysia Año: 2006 Tipo del documento: Article Pais de publicación: Malasia