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Cirrhosis associated with homozygous alpha-1 antitrypsin deficiency in the adult: a case report.
Chibbaro, G; Bartoloni Saint Omer, F; offtti, A; Nucci, A; Verdiani, V.
Afiliación
  • Chibbaro G; Unità Operativa di Gastroenterologia e Università di Firenze, Italy.
Ital J Gastroenterol ; 23(4): 216-8, 1991 May.
Article en En | MEDLINE | ID: mdl-1751819
A 34 year old woman admitted to the department of Gastroenterology of Florence hospital was diagnosed as suffering from liver cirrhosis with an alpha-1 antitrypsin deficiency (PiZZ phenotype). Liver biopsy showed the presence of intra-hepatocyte PAS-positive inclusions and the presence of alpha-1 antitrypsin was confirmed using the immunoperoxidase technique. No other organ appeared to be affected and respiratory function tests were within normal limits. The quantitative assay of alpha-1 antitrypsin was higher than values reported in the literature for PiZZ homozygotes. The authors report the case and discuss some aspects of this disease.
Asunto(s)
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Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Deficiencia de alfa 1-Antitripsina / Cirrosis Hepática Tipo de estudio: Risk_factors_studies Límite: Adult / Female / Humans Idioma: En Revista: Ital J Gastroenterol Año: 1991 Tipo del documento: Article País de afiliación: Italia Pais de publicación: Italia
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Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Deficiencia de alfa 1-Antitripsina / Cirrosis Hepática Tipo de estudio: Risk_factors_studies Límite: Adult / Female / Humans Idioma: En Revista: Ital J Gastroenterol Año: 1991 Tipo del documento: Article País de afiliación: Italia Pais de publicación: Italia